Publications
 
  • Jonathan D. Gough, Craig M. Crews: Using Natural Products to Unravel Cell Biology, Book Chapter in Chemical Biology: From Small Molecules to Systems Biology and Drug Design. Wiley Press, 2007
  • Jonathan D. Gough, Craig M. Crews: Probing Protein Function with Small Molecules. Ernst Schering Research Foundation Workshop. Chemical Genomics, 2005. 58, 61-74.
  • Jonathan D. Gough and Watson J. Lees, “ortho-and meta-Substituted Aromatic Thiols as Efficient Redox Buffer for Increasing the Folding Rate of a Disulfide Containing Protein”  Journal of Biotechnology, 2005. 125, 39-47.  pdf
  • Jonathan D. Gough and Watson J. Lees:  Increased Catalytic Activity of Protein Disulfide Isomerase (PDI) in the Presence of Aromatic Thiol Based Redox Buffers” Bioorganic Medicinal Chemistry Letters, 2005. 15, 777-781.  pdf
  • Jonathan D. Gough and Watson J. Lees, “Effects of Redox Buffer Properties on the Folding of a Disulfide Containing Protein: Dependence upon pH, Thiol pKa, and Thiol Concentration”, Journal of Biotechnology, 2005. 115, 279-290.  pdf
  • Jonathan D. Gough, Joseph M. Gargano, Anthony E. Donofrio, and Watson J. Lees, “Aromatic Thiol pKa Effects on the Folding Rate of a Disulfide Containing Protein” Biochemistry, 2003. 42, 11787-11797.  pdf
  • Jonathan D. Gough, Rhondye H. Williams, Jr., Anthony E. Donofrio, and Watson J. Lees, “Folding Disulfide-Containing Proteins Faster with an Aromatic Thiol”  Journal of the American Chemical Society, 2002. 124, 3885-3892.  pdf
  • Hassan Musa, Jonathan D. Gough, Watson J. Lees, and Richard D. Veenstra, “Ionic Blockade of the Rat Connexin40 Gap Junction Channel by Large Tetraalkylammonium Ions”  Biophysical Journal, 2001. 81, 3253-3274.  pdf
  • Jonathan D. Gough, and Lowell H. Hall, “Modeling Antileukemic Activity of Carboquinones with Electrotopological State and Chi Indices”  Journal of Chemical Information and Computer Sciences, 1999. 39, 356-361. pdf
  • Jonathan D. Gough, and Lowell H. Hall, “Modeling the Toxicity of Amide Herbicides Using the Electrotopological State”  Environmental Toxicology and Chemistry, 1999. 18, 1069-1075.

 


Information on Courses

Organic Synthesis

Chemical Biology

Publications

Jonathan Gough